Which of the following is a common organism that causes sepsis?

Sepsis is a life-threatening condition resulting from the body's response to infection and can be caused by various organisms. The correct answer highlights that several types of bacteria can be responsible for this severe reaction.

E. coli is one of the most common pathogens associated with sepsis, particularly in urinary tract infections that may lead to systemic involvement. It is known for its ability to cause infections that can quickly progress to sepsis if not addressed promptly.

Staphylococcus aureus is another significant bacterium that can lead to sepsis, especially in individuals with compromised immune systems or those with skin and soft tissue infections. It can enter the bloodstream and trigger a systemic inflammatory response, leading to sepsis.

Streptococcus pneumoniae is also a notable pathogen responsible for sepsis, particularly in cases of pneumonia, meningitis, or sinusitis, where it can breach barriers and enter the bloodstream.

Given the capabilities of all these organisms to cause sepsis, recognizing them as potential culprits is crucial for prompt diagnosis and treatment in the emergency department setting. Thus, all of the listed organisms are common causative agents in sepsis, which supports the selection of the answer indicating that all are involved.